Market Analysis and Insights:
The market for Next-Generation sequencing was estimated to be worth USD 8.3 billion in 2022, and from 2023 to 2032, it is anticipated to grow at a CAGR of 14.57%, with an expected value of USD 29.67 billion in 2032.
The market for Next-Generation Sequencing (NGS) is being propelled by various significant factors. Firstly, the rising demand for personalized medicine and targeted therapies is driving the uptake of NGS technologies. These technologies play a crucial role in enabling precision medicine by delivering precise and comprehensive genetic information. Secondly, the reduced costs associated with NGS technologies have increased their accessibility to a broader array of users, including academic institutions, research facilities, clinics, and smaller biotech companies. Moreover, the escalating incidence of chronic diseases like cancer, genetic disorders, and infectious diseases necessitates fast and effective DNA sequencing, thereby boosting the demand for NGS in clinical diagnostics and treatment monitoring. Additionally, the progress made in bioinformatics and data analysis tools has made it possible to interpret complex genomic data produced by NGS technologies, further stimulating market growth. Lastly, nerships between academic institutions, research bodies, and sequencing technology suppliers are promoting innovative applications of NGS in diverse fields such as agriculture, forensics, and environmental studies, expanding the market's scope. Combined, these factors are driving the increasing significance and expansion of the NGS market.
Next-Generation sequencing Market Scope:
| Metrics | Details |
| Base Year | 2023 |
| Historic Data | 2018-2022 |
| Forecast Period | 2024-2032 |
| Study Period | 2018-2032 |
| Forecast Unit | Value (USD) |
| Revenue forecast in 2032 | USD 29.67 billion |
| Growth Rate | CAGR of 14.57% during 2023-2032 |
| Segment Covered | By Technology, By Product, By Application, By Workflow, By End-use, By Region. |
| Regions Covered | North America, Europe, Asia Pacific, South America, Middle East and Africa |
| Key Players Profiled | Illumina Inc., Thermo Fisher Scientific Inc., Pacific Biosciences of California Inc., Oxford Nanopore Technologies Ltd., BGI Genomics Co. Ltd., Roche Holding AG, Qiagen NV, Agilent Technologies Inc., 10x Genomics Inc., and Beijing Genomics Institute (BGI). |
Market Definition
The market for next-generation sequencing is flourishing and involves innovative methods and technologies for DNA sequencing, facilitating quicker and more economical examination of genetic data. It is chiefly fueled by the need for personalized healthcare, progress in genomics studies, and expanding utility across diverse sectors like oncology, infectious diseases, and agriculture.
The significance of the Next-Generation sequencing (NGS) market lies in its transformative influence across a diverse array of research and practical domains such as genomics, personalized medicine, oncology, agriculture, and forensics. NGS represents a high-speed, precise, and cost-efficient sequencing platform capable of examining extensive DNA or RNA datasets, thereby enabling the detection of genetic discrepancies, disease-related mutations, and customized treatment modalities. This innovative technology has redefined the approach to disease investigation for scientists, uncovering novel perspectives on genetic ailments, cancer development, and infectious maladies. Moreover, NGS has been instrumental in propelling the field of precision medicine forward, empowering healthcare providers to craft individualized therapeutic strategies based on patients' unique genetic profiles.
This technology has also revolutionized agricultural practices and animal husbandry by facilitating the identification of target genes and genetic markers essential for crop enhancement and breeding programs. The NGS market serves as a cornerstone for fostering progress in scientific exploration, personalized health management, and enhancing agricultural methodologies.
Key Market Segmentation:
Insights On Key Technology
WGS
WGS is expected to dominate the Global Next-Generation sequencing Market. WGS offers comprehensive genetic information by sequencing an individual's entire genome. As sequencing technologies advance and become more cost-effective, the adoption of WGS is likely to increase.WGS has a wide range of applications in medicine, including disease diagnosis, personalized medicine, and pharmacogenomics. Its ability to provide detailed genetic information makes it invaluable in clinical settings. In the research sector, WGS is crucial for studying complex genetic traits, understanding disease mechanisms, and developing new therapeutic interventions.
Whole Exome Sequencing (WES)
Whole Exome Sequencing (WES) is a of By Technology and is one of the key players in the global Next-Generation sequencing Market. WES focuses on sequencing only the protein-coding region of the genome, which makes up a small portion of the entire genome. This targeted approach allows for a more cost-effective and efficient sequencing process, as it reduces the amount of data and analysis required compared to Whole Genome Sequencing (WGS). However, while WES has its advantages, it is not expected to dominate the market due to the growing prominence of other s.
Targeted Sequencing & Resequencing
Targeted Sequencing & Resequencing is another of By Technology that is gaining traction in the Next-Generation sequencing Market. This approach focuses on sequencing specific regions of interest in the genome, such as genes or genomic regions associated with certain diseases or conditions. Targeted sequencing provides more focused and accurate results compared to WGS or WES, making it icularly useful in research and clinical applications. However, it is unlikely to dominate the market as it is more specialized and may not be as widely adopted as other s.
Others
The "Others" encompasses various technologies and approaches that do not fall under the specific categories of WGS, WES, or targeted sequencing. These may include methods like RNA sequencing, single-cell sequencing, or methylation sequencing, among others. While these technologies have their own niche applications and are important for specific research purposes, they are not expected to dominate the overall Next-Generation sequencing Market. Due to their specialized nature and limited scope of application, the "Others" is likely to have a smaller market share compared to WGS or other dominating s.
Insights On Key Product
Platform
Platform is expected to dominate the Global Next-Generation Sequencing Market. This is because the platform plays a crucial role in the entire sequencing process, serving as the backbone for data generation and analysis. Next-generation sequencing platforms enable high-throughput sequencing, allowing researchers to obtain large volumes of genetic data in a shorter time frame. These platforms offer advanced features such as increased sequencing speed, improved accuracy, and enhanced sensitivity, making them highly sought after by research institutions, biotechnology companies, and diagnostic laboratories. Moreover, constant technological advancements and the launch of innovative platforms have further fueled the demand for next-generation sequencing platforms, positioning this as the dominant force in the Global Next-Generation Sequencing Market.
Consumables
While the Platform dominates the Global Next-Generation Sequencing Market, the Consumables also holds significant importance. Consumables refer to the various reagents, kits, and chemicals used in the sequencing process, including library preparation kits, sequencing kits, and sample multiplexing reagents. These consumables are required for each sequencing run, ensuring the accuracy and efficiency of the process. Although the Platform may overshadow the Consumables in terms of market dominance, the Consumables is essential for running sequencing experiments. As the Global Next-Generation Sequencing Market expands, the demand for consumables is expected to grow, making it a crucial within the overall market landscape.
Insights On Key Application
Reproductive Health
Based on the available data and market research, Reproductive Health is expected to dominate the Global Next-Generation Sequencing market. This can be attributed to the increasing demand for genetic screening and prenatal testing in the field of reproductive health. Next-generation sequencing technologies have revolutionized the diagnosis and detection of genetic disorders in embryos, helping couples make informed decisions regarding their reproductive choices. Additionally, the advancements in non-invasive prenatal testing (NIPT) using next-generation sequencing have significantly improved the accuracy and reliability of detecting chromosomal abnormalities in early pregnancy. Therefore, with the growing adoption of genetic testing and advancements in reproductive healthcare, Reproductive Health is projected to dominate the Global Next-Generation Sequencing market.
Oncology
Oncology holds significant potential in the Global Next-Generation Sequencing market. The use of next-generation sequencing techniques in oncology has revolutionized cancer research, diagnosis, and treatment. NGS enables the identification of genetic mutations, genomic alterations, and driver genes associated with different types of cancer, allowing for personalized and targeted therapies. With the increasing focus on precision medicine and the need for identifying specific genomic biomarkers for effective cancer treatment, Oncology is expected to play a crucial role in driving the growth of the Global Next-Generation Sequencing market.
Clinical Investigation
In the Global Next-Generation Sequencing market, Clinical Investigation is projected to contribute significantly. Next-generation sequencing has transformed clinical investigation by enabling the identification of disease-causing mutations, detection of genetic variations, and understanding the genetic basis of various diseases. This finds applications in studying rare diseases, identifying therapeutic targets, and investigating the molecular basis of complex disorders. By utilizing NGS technology, researchers can analyze large sets of genomic data to unravel the underlying mechanisms of diseases and develop targeted therapies. As the demand for precision medicine and personalized healthcare grows, Clinical Investigation is expected to have a substantial impact on the Global Next-Generation Sequencing market.
HLA Typing/Immune System Monitoring
HLA Typing/Immune System Monitoring in the Global Next-Generation Sequencing market plays a vital role in transplantation and immunology research. Next-generation sequencing offers a more comprehensive and accurate approach to HLA typing, which is crucial in organ transplantation and matching donors with recipients. Additionally, NGS technology aids in immune system monitoring, where it provides detailed insights into the diversity and dynamics of immune cells, aiding in the development of immunotherapies and monitoring treatment responses. With the increasing focus on personalized medicine and advancements in transplantation and immunological research, HLA Typing/Immune System Monitoring is expected to contribute significantly to the Global Next-Generation Sequencing market.
Metagenomics
Metagenomics holds promise in the Global Next-Generation Sequencing market. Metagenomics involves the study of genetic material derived from environmental samples, allowing for the analysis of microbial communities and their functions. Next-generation sequencing technologies have enhanced metagenomic studies by enabling high-throughput sequencing and analysis of complex microbial ecosystems. This finds applications in various fields, including environmental monitoring, understanding the human microbiome, and identifying new drug targets. As the importance of microbiota and microbial diversity in human health and the environment is increasingly recognized, Metagenomics is anticipated to play a significant role in the Global Next-Generation Sequencing market.
Epidemiology & Drug Development
In the Global Next-Generation Sequencing market, Epidemiology & Drug Development is expected to make noteworthy contributions. NGS technology allows for the rapid and cost-effective analysis of large-scale genomic data, which is crucial in epidemiological studies and drug development. By sequencing and analyzing the genomes of pathogens, researchers can gain insights into disease transmission, identify virulence factors, and develop targeted interventions. Moreover, next-generation sequencing aids in pharmacogenomics, helping to identify genetic variations that influence an individual's response to drugs. As the demand for personalized medicine and precision drug development increases, Epidemiology & Drug Development is anticipated to play a significant role in the Global Next-Generation Sequencing market.
Agrigenomics & Forensics
Agrigenomics & Forensics has significant potential in the Global Next-Generation Sequencing market. Next-generation sequencing plays a crucial role in enhancing crop productivity, studying plant genetics, and developing novel breeding strategies through agrigenomics. Additionally, NGS technology has revolutionized forensic analysis by enabling highly sensitive and accurate identification of individuals through DNA profiling. The applications of next-generation sequencing in both agrigenomics and forensics have witnessed substantial growth, and this is expected to continue driving the Global Next-Generation Sequencing market.
Consumer Genomics
Although Consumer Genomics is not expected to dominate the Global Next-Generation Sequencing market, it holds considerable significance. Consumer genomics involves genetic testing and analysis offered directly to consumers, providing insights into ancestry, disease predisposition, and personalized health. While the market for consumer genomics continues to grow, it is relatively smaller compared to other s within the Global Next-Generation Sequencing market. Nonetheless, as awareness and interest in personal genetics increase, Consumer Genomics is expected to play a significant role in shaping the market dynamics.
Insights On Key Workflow
NGS Data Analysis
NGS Data Analysis is expected to dominate the Global Next-Generation Sequencing Market. This is because NGS Data Analysis plays a crucial role in interpreting and extracting meaningful insights from the vast amount of sequencing data generated during the NGS process. With advancements in bioinformatics and data analysis techniques, the demand for efficient and accurate NGS Data Analysis solutions is increasing. By analyzing the sequencing data, researchers can uncover genetic variations, identify disease-causing mutations, and gain insights into complex biological processes. This 's dominance is supported by the growing adoption of NGS technologies in various applications such as precision medicine, cancer genomics, and agricultural research.
Pre-Sequencing
While NGS Data Analysis is expected to dominate the market, the Pre-Sequencing also holds significance in the Global Next-Generation Sequencing Market. Pre-Sequencing encompasses sample preparation, library construction, and target enrichment techniques. These steps are crucial for ensuring high-quality sequencing data and efficient utilization of NGS instruments. With the increasing demand for higher throughput and accuracy in sequencing, the importance of robust Pre-Sequencing workflows cannot be undermined. The development of innovative sample preparation kits, automation systems, and target enrichment methods further strengthens the growth potential of this .
Sequencing
Sequencing, being an integral of the NGS workflow, also plays a vital role in the Global Next-Generation Sequencing Market. However, it may not dominate the market as compared to NGS Data Analysis or Pre-Sequencing s. The sequencing primarily includes the actual generation of DNA or RNA sequences using various sequencing platforms and technologies. While advancements in sequencing technologies such as Illumina, PacBio, and Oxford Nanopore have revolutionized the field, the market is highly competitive with several players offering similar sequencing solutions. Nonetheless, continuous improvements in sequencing speed, accuracy, and affordability are anticipated to propel the growth of this .
In conclusion, based on the data and analysis, the NGS Data Analysis is expected to dominate the Global Next-Generation Sequencing Market. However, the Pre-Sequencing and Sequencing s also hold significant importance, contributing to the overall growth of the market.
Insights On Key End-use
Pharma & Biotech Entities
Pharma & Biotech Entities is expected to dominate the Global Next-Generation sequencing Market Market. With the rising demand for personalized medicine and precision oncology, pharmaceutical and biotech companies are increasingly adopting next-generation sequencing (NGS) technology. NGS enables these entities to analyze genomic data more efficiently, identify disease-related biomarkers, develop targeted therapies, and carry out clinical trials. Moreover, the advancement in NGS technology has made it more cost-effective and accessible to these entities. Thus, the Pharma & Biotech Entities is projected to be the dominant end-user in the Global Next-Generation sequencing Market Market.
Academic Research
Academic research institutions are another significant end-user of next-generation sequencing technology. These institutions play a crucial role in advancing genomic research, studying genetic variations, and discovering disease associations. They primarily utilize NGS for understanding genetic disorders, conducting population studies, and exploring disease mechanisms. Moreover, academic researchers often collaborate with healthcare providers and pharmaceutical companies to translate their findings into clinical applications. Although academic research institutions have a vital role in advancing NGS technology, they are expected to have a lesser market share compared to Pharma & Biotech Entities due to the higher commercial adoption by the latter.
Hospitals & Clinics
Hospitals and clinics are increasingly recognizing the benefits of next-generation sequencing in diagnosing and treating various diseases. NGS technology enables healthcare providers to carry out comprehensive genetic testing, identify inherited diseases, detect early-stage cancer biomarkers, and personalize treatment plans. However, due to the complexities associated with implementing NGS infrastructure, data analysis, and reimbursement challenges, the Hospitals & Clinics may have a smaller market share compared to Pharma & Biotech Entities and Academic Research institutions.
Clinical Research
The Clinical Research utilizes next-generation sequencing technology for conducting research studies focused on developing new therapies, evaluating treatment efficacy, and understanding disease progression. By leveraging NGS, clinical research organizations can perform genetic profiling, identify potential drug targets, and assess the impact of genetic variations on drug response. While clinical research plays a crucial role in contributing to scientific knowledge and advancing clinical practice, it may have a relatively smaller market share compared to the dominant of Pharma & Biotech Entities.
Other Users
The Other Users encompasses various end-users, such as government research organizations, non-profit institutions, and forensic laboratories. These users utilize NGS technology for a wide range of applications, including forensic DNA analysis, agricultural research, environmental studies, and microbiome research. Although their contribution to the overall market is essential, the Other Users is expected to have a smaller market share compared to Pharma & Biotech Entities, Academic Research, Hospitals & Clinics, and Clinical Research institutions.
Insights on Regional Analysis:
Europe is expected to dominate the Global Next-Generation sequencing (NGS) Market. The region's dominance can be attributed to several key factors. Firstly, Europe houses a large number of prominent players in the NGS market, including Illumina, Thermo Fisher Scientific, and Qiagen, among others. These companies have established a strong presence in Europe and have a wide customer base, contributing to the overall growth of the market. Additionally, Europe has a well-developed healthcare infrastructure and a high adoption rate of advanced technologies, including NGS. The region also has significant government support and funding for genomics research and precision medicine, further accelerating the market growth. With these favorable conditions, Europe is poised to dominate the Global NGS Market.
North America has a strong presence in the Global NGS Market as well. The region boasts a technologically advanced healthcare system and a significant number of research institutes and academic centers. The presence of key market players such as Illumina and Pacific Biosciences also contributes to the dominance of North America in the market. Furthermore, the region has a high demand for NGS technologies in various applications, including oncology, genetic disorders, and infectious diseases. These factors position North America as a prominent player in the Global NGS Market.
Asia Pacific is emerging as a lucrative market for NGS technology due to its large population and increasing healthcare expenditure. The region's growing focus on precision medicine, genomics research, and personalized healthcare is driving the demand for NGS technologies. Additionally, countries like China and India are witnessing rapid advancements in genomics research and are making substantial investments in healthcare infrastructure. Consequently, Asia Pacific presents significant growth opportunities for NGS companies, making it a promising market in the Global NGS Market.
Latin America has seen gradual growth in the adoption of NGS technologies. Factors such as increasing awareness about genetic diseases, improving healthcare infrastructure, and rising collaborations between research institutions and sequencing providers are driving the market in the region. While the market is still developing, Latin America has the potential to become an important player in the Global NGS Market.
The Middle East & Africa region is currently at a nascent stage in terms of NGS adoption. Limited infrastructure and funding for genomics research, along with low awareness about NGS technologies, pose challenges to market growth. However, with the growing prevalence of genetic disorders and increasing investments in healthcare infrastructure, the region holds potential for future growth in the NGS market.
Company Profiles:
Prominent figures in the worldwide Next-Generation Sequencing industry are crucial contributors to the progression of genetic exploration and precision healthcare by creating and introducing sequencing platforms, reagents, and bioinformatics resources. Illumina, Thermo Fisher Scientific, and Pacific Biosciences are among the key figures in this sector, spearheading innovation and market dynamics to encourage the broad acceptance of sequencing techniques across diverse fields.
Prominent companies in the Next-Generation Sequencing (NGS) industry include Illumina Inc., Thermo Fisher Scientific Inc., Pacific Biosciences of California Inc., Oxford Nanopore Technologies Ltd., BGI Genomics Co. Ltd., Roche Holding AG, Qiagen NV, Agilent Technologies Inc., 10x Genomics Inc., and Beijing Genomics Institute (BGI). These organizations are dedicated to developing, producing, and marketing a variety of NGS platforms, tools, and services. Their focus revolves around innovation to enhance the efficiency, precision, and cost-effectiveness of NGS technologies, providing researchers and scientists with accelerated and in-depth analysis of DNA and RNA samples. With comprehensive product offerings and a strong market presence, these industry leaders are propelling the global growth and progress of the Next-Generation Sequencing market.
Key Segments of the Next-Generation Sequencing Market
Technology Overview
• WGS (Whole Genome Sequencing)
• Whole Exome Sequencing
• Targeted Sequencing & Resequencing
• Others
Product Overview
• Platform
• Consumables
Application Overview
• Oncology
• Clinical Investigation
• Reproductive Health
• HLA Typing/Immune System Monitoring
• Metagenomics
• Epidemiology & Drug Development
• Agrigenomics & Forensics
• Consumer Genomics
Workflow Overview
• Pre-Sequencing
• Sequencing
• NGS Data Analysis
End-Use Overview
• Academic Research
• Clinical Research
• Hospitals & Clinics
• Pharma & Biotech Entities
• Other Users
Regional Overview
North America
• US
• Canada
• Mexico
Europe
• Germany
• France
• U.K
• Rest of Europe
Asia Pacific
• China
• Japan
• India
• Rest of Asia Pacific
Middle East and Africa
• Saudi Arabia
• UAE
• Rest of Middle East and Africa
Latin America
• Brazil
• Argentina
• Rest of Latin America
Frequently Asked Questions (FAQ) :
The application of the next generation sequencing market Oncology, Clinical Investigation, Reproductive Health, HLA Typing/Immune System Monitoring, Metagenomics, Epidemiology & Drug Development, Agrigenomics & Forensics, Consumer Genomics.
The top companies that hold the market share in next generation sequencing market are Illumina Inc., Thermo Fisher Scientific Inc., Pacific Biosciences of California Inc., Oxford Nanopore Technologies Ltd., BGI Genomics Co. Ltd., Roche Holding AG, Qiagen NV, Agilent Technologies Inc., 10x Genomics Inc., and Beijing Genomics Institute (BGI).
The global next generation sequencing market is segmented on the By Technology, By Product, By Application, By Workflow, By End-use, By Region.